Fatigue, Durability, and Muscle Damage in Ultra Running with Prof Guillaume Millet and Prof Paul Laursen

Fatigue, Durability, and Muscle Damage in Ultra Running with Prof Guillaume Millet and Prof Paul Laursen

February 14, 2026

Listen to the episode now or find us on Spotify and Apple Podcasts.

Show Notes

Show notes

  1. What fatigue actually means
    Why we should stop using one word for everything, the difference between chronic fatigue and exercise fatigability, and how each one is measured.
  2. Durability vs fatigability, and why the debate matters
    The key difference is time, why an MVC can look “recovered” while the athlete is not, and how older models already captured what durability is trying to describe.
  3. Muscle damage as the ultra limiter
    Why eccentric load and soreness drive perceived effort, what repeated bout effect changes, and why targeted downhill work can completely change race outcomes.

Practical tools and ideas that change outcomes
Shock weekends for specific resilience, how heat mainly hits perceived exertion. Plus innovative monitoring tools like Myocene and where to learn more at https://www.kinesiologui.com.

You May Also Like…

Level-Up

Featured Courses

Metabolic Conditioning🔥for Team Sports!

In team sports, it's not about running more, it's about WINNING.
This MASTER CLASS teaches you how to build the
PHYSIOLOGICAL BASE that supports training and matches.

➡️ GET IT HERE! ⬅️

& sign up below for the HIIT Science Newsletter!

Please check your email inbox and confirm your participation.