Fatigue, Durability, and Muscle Damage in Ultra Running with Prof Guillaume Millet and Prof Paul Laursen

Fatigue, Durability, and Muscle Damage in Ultra Running with Prof Guillaume Millet and Prof Paul Laursen

February 14, 2026

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Show Notes

Show notes

  1. What fatigue actually means
    Why we should stop using one word for everything, the difference between chronic fatigue and exercise fatigability, and how each one is measured.
  2. Durability vs fatigability, and why the debate matters
    The key difference is time, why an MVC can look “recovered” while the athlete is not, and how older models already captured what durability is trying to describe.
  3. Muscle damage as the ultra limiter
    Why eccentric load and soreness drive perceived effort, what repeated bout effect changes, and why targeted downhill work can completely change race outcomes.

Practical tools and ideas that change outcomes
Shock weekends for specific resilience, how heat mainly hits perceived exertion. Plus innovative monitoring tools like Myocene and where to learn more at https://www.kinesiologui.com.

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